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Inhibition of Soluble Stem Cell Factor Promotes Intestinal Mucosal Repair.

Vicky Garcia-Hernandez,Arturo Raya-Sandino,Veronica Azcutia,Jael Miranda,Matthias Kelm,Sven Flemming, Dorothee Birkl,Miguel Quiros,Jennifer C Brazil,Charles A Parkos,Asma Nusrat

Inflammatory bowel diseases（2023）

Cited 0|Views15
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Abstract
These data demonstrate that SCF functions as a pro-inflammatory mediator in mucosal tissues and that specific neutralization of SCF248 could be a viable therapeutic option to reduce intestinal inflammation and promote mucosal wound repair in individuals with IBD.
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Key words
IBD,epithelia,intestine,mucosal repair,pro-inflammatory cytokine
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