Search
ChatPaper
AI Writing
analysis
Analysis
编组
Open Data
more
More
RankingsMust ReadingJournal&ConferenceAI TRAI HistoryMaster Reading TreeXiaomai's Star TalentsTrajectoryTalentNDI TrackerOpenAI sign Language
VIPCreated with Sketch.

Secreted Factors Determine Resistance To Idelalisib In Splenic Marginal Zone Lymphoma (Mzl) Models

A. J. Arribas,S. Napoli,L. Cascione,G. Sartori,E. Gaudio,C. Tarantelli,A. A. Mensah,F. Spriano,A. Zucchetto,F. M. Rossi,A. Rinaldi, S. Jovic,A. Stathis,G. Stussi,V. Gattei,J. R. Brown, M. Esteller,E. Zucca,D. Rossi,F. Bertoni

ANNALS OF ONCOLOGY（2021）

Cited 0|Views4
No score
Abstract
PI3Kδ has a central role in the BCR signaling in hematological malignancies. Idelalisib was the first-in-class PI3Kδ inhibitor, and several novel compounds are undergoing clinical investigation. To identify modalities to overcome the resistance developed to these agents, we have developed idelalisib-resistant models derived from MZL cell lines.
More
Translated text
Key words
splenic marginal zone lymphoma
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined