During his career he has worked in Milan (Ospedale Maggiore Policlinico and “Mario Negri” Institute of Pharmacological Research), London (Institute of Child Health and The Barts and The London) and in Ticino (Servizio Oncologico Cantonale). Since April 2003, he has been leading his group is in Bellinzona. Since 2019 he is the President of the Local Organizing Committee of the International Conference on Malignant Lymphoma (ICML). Since January 2009 he is the Editor-in-Chief of Hematological Oncology. Bertoni has supervised several Master and PhD students. Bertoni actively participates to Swiss Cancer Research Group (SAKK), in which he is the President of the Project Group Lymphoma and member of the Project Group Developmental Therapeutics. Prof. Bertoni is the author or co-author of over 200 original papers, over 50 editorials or invited reviews, 20 book sections, one edited book and several abstracts at national and international meetings.