Ultrafast 4D Doppler Imaging of the Rat Brain with a Large Aperture Row Column Addressed Probe

4D ultrafast imaging has been recently introduced to provide new anatomical, mechanical and functional information. It relies on 2-D matrix array to image the medium at high volume rate and quantify blood flow information. However, this approach requires high channel count electronics (NxN) to drive those probes. An alternative to reduce the density of elements and maintain a decent image at very high volume rate was shown using the Row and Column Addressed (RCA) approach with Orthogonal Plane Wave (OPW) compounding strategy. Furthermore, the RCA configuration presents the advantage of keeping a large surface by reducing the count of channel by a factor N/2. In this study, we designed and built a large 15 MHz 256 channels (128+128) probe dedicated to neurovascular imaging and connected to a 256 channels research electronics. Using OPW image strategy, 4D ultrafast Power Doppler of whole rat brain is performed in vivo with a 23dB dynamic range at 125 Hz on whole brain.