Machine Learning-Driven Prediction of Immune Checkpoint Inhibitor Responses Against Cholangiocarcinoma: a Bile Biopsy Perspective

Dengyong Zhang, Xinrui Li, Zhonglin Wang, Jingyuan Fan, Yuhang Yang, Sophia Han,Wanliang Sun,Dongdong Wang,Shuo Zhou, Zhong Liu, Shihao Chen, Yan Yang, Yan Zhu,Zheng Lu

Frontiers in Immunology（2025）

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cholangiocarcinoma,immune checkpoint inhibitors,bile metabolomics,machine learning,programmed cell death protein 1 (PD-1) therapy,immune hot-cold index

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