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AP1-mediated Reprogramming of EGFR Expression Triggers Resistance to BLU-667 and LOXO-292 in RET-rearranged Tumors

Daniela Esposito, Claudia Maria Ascione, Stefania Belli,Fabiana Napolitano,Alberto Servetto, Felice Pepe,Umberto Malapelle,Antonino Iaccarino,Giancarlo Troncone, Diletta Barone,Emilio Bria,Roberto Ferrara,Daniele Lorenzini,Giuseppe Lo Russo,Maria Rosa Ghigna,Arianna Marinello,Mihaela Aldea,Benjamin Besse,Luigi Formisano,Roberto Bianco

Journal of Experimental & Clinical Cancer Research（2025）

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Key words
Non-small cell lung cancer,RET,RET inhibitors,EGFR,Drug resistance,Combination targeted therapy
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