Molecular Signatures of Xenograft Colorectal Cancer in Mice Treated with Topotecan: A Mass Spectrometry-Based Study

Yousra A Hagyousif, Ruba A Zenati,Nelson C Soares, Hamza M Al-Hroub, Farman Matloob Khan,Rizwan Qaisar,Rifat Hamoudi,Raafat El-Awady,Ahmad Y Abuhelwa, Wafaa Ramadan,Waseem El-Huneidi, Eman Abu-Gharbieh,Karem H Alzoubi,Yasser Bustanji, Mohammad H Semreen

Toxicology reports（2025）

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Key words

Colorectal cancer,Topotecan,Metabolomics,LC-MS/MS-QTOF

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