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Hipsc-Neurons Recapitulate the Subtype-Specific Cell Intrinsic Nature of Susceptibility to Neurodegenerative Disease-Relevant Aggregation

Ian Weidling, Christina N. Preiss, Sarah E. Chancellor, Gyan Srivastava, Lauren Gibilisco, Gen Lin, Melanie Shackett Brennan, Janice Lee, Lindsay M. Roth, Olga Morozova, Kyong Nyon Nam, Nehal R. Patel, Qing Liu, J. K. Thomas,Peter Reinhardt, Ruven Wilkens,Dagmar E. Ehrnhoefer,Andreas Striebinger,Stefan Barghorn, Christina Xanthopoulos, Marie-Theres Weil, Sandra Biesinger,Miroslav Cik, Nandini Romanul,Kiran Yanamandra, Alessandra M. Welker, Jessica Wu,Laura Gasparini, Jan Stöhr, Xavier Langlois, Justine D. Manos

Acta Neuropathologica Communications(2025)

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关键词
hiPSC-derived neurons,Selective vulnerability,Tau,Alzheimer’s disease,Parkinson’s disease
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