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Custom CRISPR—Cas9 PAM Variants Via Scalable Engineering and Machine Learning

Rachel A Silverstein, Nahye Kim, Ann-Sophie Kroell, Russell T Walton, Justin Delano, Rossano M Butcher, Martin Pacesa, Blaire K Smith, Kathleen A Christie, Leillani L Ha, Ronald J Meis, Aaron B Clark, Aviv D Spinner,Cicera R Lazzarotto,Yichao Li, Azusa Matsubara, Elizabeth O Urbina, Gary A Dahl, Bruno E Correia, Debora S Marks,Shengdar Q Tsai,Luca Pinello, Suk See De Ravin,Qin Liu,Benjamin P Kleinstiver

Nature(2025)

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