Use of a Silicon Microneedle Chip-Based Device for the Extraction and Subsequent Analysis of Dermal Interstitial Fluid in Heart Failure Patients

Markus Renlund, Laurenz Kopp Fernandes, Pelle Rangsten, Mikael Hillmering, Sara Mosel, Ziad Issa,Volkmar Falk,Alexander Meyer,Felix Schoenrath

Diagnostics (Basel, Switzerland)（2025）

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Key words

microneedle,dermal interstitial fluid,biomarkers,high-sensitivity CRP,NT-proBNP,lactate,biomarker kinetics,inflammation,heart failure,micro-electro-mechanical systems (MEMS)

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