Maplirpacept: a CD47 Decoy Receptor with Minimal Red Blood Cell Binding and Robust Anti-Tumor Efficacy

Mithunah Krishnamoorthy, Ruth Seelige, Christopher R Brown, Nancy Chau,Natasja Nielsen Viller,Lisa D S Johnson,Emma Linderoth,Jean C Y Wang,Christopher P Dillon, Keith Abayasiriwardana, Clare Lees,Mark Wong, Megan M Kaneda,Robert A Uger,Gloria H Y Lin

Frontiers in immunology（2025）

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Key words

CD47,phagocytosis,red blood cells,hematological malignances,SIRP alpha

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