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Paired Primary-Metastasis Patient-Derived Organoids and Mouse Models Identify Phenotypic Evolution and Druggable Dependencies of Peritoneal Metastasis from Appendiceal Cancer

Ahmed Mahmoud, Philip H Choi, Christine Sukhwa, Jura Pintar,Henry Walch, Nan Zhao,Jonathan Bermeo,Sebastian Chung, Manisha Raghavan,Samhita Bapat,Qingwen Jiang,Georgios Karagkounis, Julia Meredith, Michael Giarrizzo,Canan Firat,Andrea Cercek,Michael B Foote,Nikolaus Schultz,Walid K Chatila,Garrett M Nash,Jinru Shia,Francisco Sanchez-Vega,Steven Larson, Arvin C Dar,Neal Rosen,Karuna Ganesh

bioRxiv the preprint server for biology（2025）

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