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Single-cell Multiome and Spatial Profiling Reveals Pancreas Cell Type-Specific Gene Regulatory Programs Driving Type 1 Diabetes Progression

Rebecca Melton, Sara Jimenez,Weston Elison, Luca Tucciarone, Abigail Howell,Gaowei Wang, Denise Berti,Elisha Beebe,Michael Miller,Chun Zeng,Carolyn McGrail, Kennedy VanderStel,Katha Korgaonkar,Ruth Elgamal,Hannah Mummey,Joshua Chiou,Emily Griffin,Irina Kusmartseva,Mark Atkinson,Sebastian Preissl,Fabian J Theis,Maike Sander,Kyle J Gaulton

bioRxiv the preprint server for biology（2025）

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