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Test of Rapamycin in Aging Dogs (TRIAD): Study Design and Rationale for a Prospective, Parallel-Group, Double-Masked, Randomized, Placebo-Controlled, Multicenter Trial of Rapamycin in Healthy Middle-Aged Dogs from the Dog Aging Project.

Amanda E Coleman,Kate E Creevy,Rozalyn Anderson,May J Reed, Virginia R Fajt,Kathleen M Aicher, Genna Atiee, Brian G Barnett,Ryan D Baumwart,Beth Boudreau,Suzanne M Cunningham,Matthew D Dunbar, Bobbie Ditzler, Anna M Ferguson,Kiersten K Forsyth, Anya N Gambino,Sonya G Gordon, Hillary K Hammond, Sydney N Holland, Mary K Iannaccone, Kate Illing,Saki Kadotani, Shelby A Knowles,Evan L MacLean, Brian A Maran,Lauren E Markovic,Stephanie McGrath, Rachel L Melvin, Mikaela S Mueller,O Lynne Nelson,Natasha J Olby, Theresa E Pancotto,Elizabeth Parsley,Brianna M Potter, Jena O Prescott,Ashley B Saunders, Holly M Sawyer,Brian A Scansen,Sarah M Schmid, Courtney C Smith,Sonja S Tjostheim,M Katherine Tolbert,Melissa A Tropf,Lance C Visser,Jessica L Ward,Sonya R Wesselowski, Rebecca C Windsor,Vicky K Yang,Audrey Ruple,Daniel E L Promislow,Matt Kaeberlein, Dog Aging Project Consortium

GeroScience(2025)

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