Spatial Transcriptomics Uncovers Hybrid, Pro-Inflammatory and Pro-Fibrotic Cellular Niches in Pulmonary Granuloma of Patients with Chronic Sarcoidosis

Leonard Christian,Hande Yilmaz,Jannik Ruwisch, Leon Giercke,Benjamin Seeliger, Jan-Christopher Kamp, Sirvan Bayraktar,Raphael Ewen,Theresa Graalmann, Jan Fuge, Mark Greer, Fabio Ius,Tobias Welte,Jens M. Hohlfeld, Marius M. Hoeper, Jens Gottlieb,Naftali Kaminski, Antje Prasse,Danny Jonigk, Yang Li, Christine Falk,Lavinia Neubert,Jonas Christian Schupp

biorxiv（2025）

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