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Mechanisms of NLRP3 Activation and Inhibition Elucidated by Functional Analysis of Disease-Associated Variants

Shouya Feng, Matthew C. Wierzbowski,Katja Hrovat-Schaale, Andreas Dumortier, Yaoyuan Zhang, Maria Zyulina,Paul J. Baker,Thomas Reygaerts,Annemarie Steiner,Dominic De Nardo, Dhanya Lakshmi Narayanan,Florian Milhavet,Alberto Pinzon-Charry,Juan Ignacio Arostegui, Raju P. Khubchandani,Matthias Geyer,Guilaine Boursier,Seth L. Masters

NATURE IMMUNOLOGY(2025)

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