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Model-Informed Selection of the Recommended Phase 2 Dosage for Anti-TIGIT Immunotherapy Leveraging Co-Expressed PD-1 Inhibitor Target Engagement.

Irina Kareva, Ping Hu, Vadryn Pierre,Thomas Kitzing,Anja Victor, Emilia Richter, Wei Gao,Karthik Venkatakrishnan,Anup Zutshi

Clinical pharmacology and therapeutics(2025)

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