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HMGB1-mediated Macrophage Regulation of NF-κB Activation and MMP3 Upregulation in Nucleus Pulposus Cells: A Critical Mechanism in the Vicious Cycle of Intervertebral Disc Degeneration

Shixin Lu,Ming Li, Ziying Cheng, Yuwei Liang,Junshen Huang, Jiajun Huang, Kun Wang,Dengbo Yao,Enming Chen,Peng Wang, Yuxi Li,Lin Huang

Cellular signalling（2025）

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关键词
Intervertebral disc degeneration,HMGB1,Macrophages,NF-κB,MMP3
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