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Transient Lymphocyte Count Decrease Correlates with Oncolytic Adenovirus Efficacy in Humans: Mechanistic and Biomarker Findings from TUNIMO Phase I Trial

Santeri A. Pakola,James H. A. Clubb,Tatiana Kudling,Mirte van der Heijden,Elise Jirovec,Victor Arias,Lyna Haybout,Katriina Peltola,Tuomo Alanko,Jorma Sormunen,Teijo Pellinen,Kristian Taipale,Dafne C. A. Quixabeira,Claudia Kistler,Riikka Havunen,Suvi Sorsa,Joao M. Santos,Victor Cervera-Carrascon,Akseli Hemminki

JOURNAL FOR IMMUNOTHERAPY OF CANCER（2025）

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Key words

Oncolytic virus,Biomarker,Solid tumor,Gene therapy

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