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Pharmacokinetic and Exposure-Response Modeling Support Body Surface Area-Based Dosing of Farletuzumab Ecteribulin in Japanese Patients with Solid Tumors

Seiichi Hayato,Lora Hamuro,Toshio Shimizu,Kan Yonemori,Shin Nishio,Mayu Yunokawa,Tatsuya Yoshida,Makoto Nishio,Koji Matsumoto,Kazuhiro Takehara,Kosei Hasegawa,Toshiyuki Kozuki,Yasuyuki Hirashima,Hidenori Kato,Takuma Miura,Maiko Nomoto, Yue Zhao,Li Zhu,Sanae Yasuda

JOURNAL OF CLINICAL PHARMACOLOGY（2025）

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关键词
antibody-drug conjugate,dose optimization,exposure-response analysis,ovarian cancer,population pharmacokinetics
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