M2 Macrophages Regulate Nucleus Pulposus Cell Extracellular Matrix Synthesis Through the OPN-CD44 Axis in Intervertebral Disc Degeneration

Zhiwen Tao, Tianyou Zhang, Yaning Ge, Lingzhi Li,Cheng Ma, Zhengbo Wang, Tong Chen,Helong Zhang, Ruya Li, Tao Jiang,Yongxin Ren

Osteoarthritis and Cartilage（2025）

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Key words

Intervertebral disc degeneration,Macrophage,Nucleus pulposus cell,Coculture,OPN,CD44

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