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Actions of Dexmedetomidine in Regulating NLRP3 in Postoperative Cognitive Dysfunction in Aged Mice Via the Autophagy-Lysosome Pathway

Zhi Wang, Li-na Zhang,Ting Wu, Xu Pan,Le Li,Xin Yang,Miao Zhang,Ying Liu,Yong Liu

BRITISH JOURNAL OF PHARMACOLOGY(2025)

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关键词
astrocyte A1 differentiation,autophagy-lysosome pathway,dexmedetomidine,microglial activation,NLRP3 inflammasome,postoperative cognitive dysfunction,TFEB
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