Peficitinib Suppresses Diffuse-Type Tenosynovial Giant Cell Tumor by Targeting TYK2 and JAK/STAT Signaling

Shan Lu,Chenxi Cao, Wenjia Zhang,Jiayi Li,Jingli Yang, Zisheng Huang, Zhijun Wu, Baitao Liu,Hongjie Huang, Haijun Wang, Yongjian Wang,Dingge Liu, Zhihua Zhang, Kaiping Liu, Gang Yang, Xi Gong, Hui Dai, Yingjia Li,Erdan Dong,Xin Zhang,Yan Zhang

Science China Life Sciences（2025）

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Key words

dTGCT,JAK/STAT signaling,peficitinib,TYK2,FLS,macrophages

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