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Structure-Based Discovery of Novel Diarylpyrimidines As Potent and Selective Non-Nucleoside Reverse Transcriptase Inhibitors: from CH(CN)-Biphenyl-Diarylpyrimidines to C=NNH2-Biphenyl-Diarylpyrimidines

Xiao-Mei Chen,Christophe Pannecouque,Erik De Clercq, Yu-Xuan Lian,Angela Corona, Laura Dettori,Enzo Tramontano,Shuai Wang,Fen-Er Chen

European journal of medicinal chemistry（2025）

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AIDS,HIV-1,NNRTIs,DAPYs
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