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Loading of CAR‐T Cells with Magnetic Nanoparticles for Controlled Targeting Suppresses Inflammatory Cytokine Release and Switches Tumor Cell Death Mechanism

Felix Pfister,Lucas R. Carnell, Lisa Loeffler, Philipp Boosz,Niels Schaft,Jan Doerrie,Rene Stein, Malte Lenz,Erdmann Spiecker, Christian M. Huber, Sami Haddadin, Carola Berking,Christoph Alexiou,Christina Janko

MEDCOMM(2025)

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关键词
adoptive T cell therapy,cancer,CAR-T cell,magnetic cell targeting,pyroptosis,superparamagnetic iron oxide nanoparticles (SPIONs)
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