Collagen Deposition in Lung Parenchyma Driven by Depletion of Interstitial Lyve-1+ Macrophages Prevents Cigarette Smoke-Induced Emphysema and Loss of Airway Function

Yinebeb Mezgebu Dagnachew,Hwee Ying Lim,Liao Wupeng,Sheau Yng Lim, Sheng Jie Natalie Lim,Chung Hwee Thiam, Shu Wen Tan, Joan Lau Joo Eng, Dan Mei, Syaza Mohammad Hazwany Azhar, Wei Siong Ong,Qi Hui Caris Tan,Wai-Shiu Fred Wong,Veronique Angeli

FRONTIERS IN IMMUNOLOGY（2025）

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macrophage,chronic obstructive pulmonary disease,collagen,extracellular matrice (ECM),Lyve-1 macrophage

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