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Maternal Phthalates Exposure Promotes Neural Stem Cell Differentiation into Phagocytic Astrocytes and Synapse Engulfment Via IRE1α/XBP1s Pathway

Fengzhen Cui, Shiyu Deng, Yan Fu, Tongtong Xu,Shuangshuang Bao,Siyi Wang,Yahang Lin, Xianghui Wang,Faming Zhao,Tingting Zhang,Shunqing Xu,Zhijun Zhang, Wanlu Li,Guo-Yuan Yang,Huanwen Tang,Jixian Wang,Xia Sheng,Yaohui Tang

Cell Reports（2025）

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Key words
monobutyl phthalate,neurodevelopmental deficit,neural stem cells,synapse phagocytosis,XBP1s,reactive astrocyte
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