SPP1-ITGα5/β1 Accelerates Calcification of Nucleus Pulposus Cells by Inhibiting Mitophagy Via Ubiquitin-Dependent PINK1/PARKIN Pathway Blockade

Hanwen Gu, Qi Li,Zhenchuan Liu, Yanlin Li,Kaiwen Liu, Xiangzhen Kong,Yuanqiang Zhang,Qunbo Meng, Kangle Song, Qing Xie, Yuan Gao,Lei Cheng

Advanced science (Weinheim, Baden-Wurttemberg, Germany)（2024）

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关键词

calcification,integrin alpha 5 beta 1,intervertebral disc degeneration,mitophagy,nucleus pulposus cells,secreted phosphoprotein 1

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