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Solid Predominant Histology and High Podoplanin Expression in Cancer-Associated Fibroblast Predict Primary Resistance to Osimertinib in EGFR-mutated Lung Adenocarcinoma

Yuji Uehara,Hiroki Izumi,Tetsuro Taki,Tetsuya Sakai,Hibiki Udagawa,Eri Sugiyama,Shigeki Umemura,Yoshitaka Zenke,Shingo Matsumoto,Kiyotaka Yoh, Shoko Kubota,Keiju Aokage,Naoya Sakamoto,Shingo Sakashita,Motohiro Kojima,Michiko Nagamine,Yukio Hosomi,Masahiro Tsuboi,Koichi Goto, Genichiro Ishi

JTO Clinical and Research Reports（2024）

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Key words
Solid predominant subtype,Lung adenocarcinoma,EGFR mutation: Cancer associated fibroblasts (CAFs),Podoplanin
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