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Metabolic Expression Profiling Analysis Reveals Pyruvate-Mediated EPHB2 Upregulation Promotes Lymphatic Metastasis in Head and Neck Squamous Cell Carcinomas

Jingjing Miao,Boyu Chen, Lu Zhang,Zhongming Lu, Rui Wang,Chunyang Wang,Xingyu Jiang, Qi Shen,Yue Li,Dongni Shi,Ying Ouyang,Xiangfu Chen, Xiaowu Deng,Siyi Zhang,Hequn Zou,Shuwei Chen

Journal of Translational Medicine（2025）

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Key words
Head and neck squamous cell carcinoma,Lymphatic metastasis,Pyruvate metabolism,EPHB2,Lymphangiogenesis
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