Discovery of VU0467319: an M1 Positive Allosteric Modulator Candidate That Advanced into Clinical Trials
Michael S. Poslunsey,Michael R. Wood,Changho Han,Shaun R. Stauffer,Joseph D. Panarese,Bruce J. Melancon,Julie L. Engers,Jonathan W. Dickerson,Weimin Peng,Meredith J. Noetzel,Hyekyung P. Cho,Alice L. Rodriguez,Corey R. Hopkins,Ryan Morrison,Rachel D. Crouch,Thomas M. Bridges,Anna L. Blobaum,Olivier Boutaud,J. Scott Daniels, Michael J. Kates, Arlindo Castelhano,Jerri M. Rook,Colleen M. Niswender,Carrie K. Jones,P. Jeffrey Conn,Craig W. Lindsley ACS CHEMICAL NEUROSCIENCE（2024）
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muscarinic acetylcholinereceptor subtype 1 (M-1),positive allosteric modulator(PAM),cognition,metabolism
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