Discovery and Optimization of Tetrahydroacridine Derivatives As a Novel Class of Antibiotics Against Multidrug-Resistant Gram-positive Pathogens by Targeting Type I Signal Peptidase and Disrupting Bacterial Membrane
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY（2025）
关键词
Tetrahydroacridine derivatives,Novel antibiotics,Antimicrobial resistance,SPase I,Bacterial membrane
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