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Comprehensive Host Cell Proteins Profiling in Biopharmaceuticals by A Sensitivity Enhanced Mass Spectrometry Strategy Using TMT-labeling and Signal Boosting

Andong Xue, Linlin Kong, Jialin Li, Yuxin Jiao,Zhishang Hu,Bin Fu, Guibin Wang,Wanjun Zhang,Jianheng Li,Weijie Qin

ANALYTICA CHIMICA ACTA(2025)

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Key words
Proteomics,Mass spectrometry,Enrichment,Host cell proteins,Biopharmaceuticals
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