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Network Pharmacology Combined with Transcriptomics Reveals That Formononetin, a Biologically Component of Astragalus Membranaceus (fisch.) Bunge, Inhibits the PI3K/Akt Signaling Pathway to Improve Chronic Renal Failure

Hongyu Luo, Shuxian Yang, Peng Deng,Yongbo Peng, Zhiwei Chen,Congwen Yang,Meng Wang, Renjie Qin, Lin Yuan,Xin Chen,Dandan Wang,Xuekuan Huang,Jianwei Wang

JOURNAL OF ETHNOPHARMACOLOGY（2025）

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关键词
Formononetin,Chronic renal failure,Anti-Fibrosis,Anti-inflammatory,PI3K/Akt signaling pathway
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