Discovery of Reversible and Covalent TEAD 1 Selective Inhibitors MSC-1254 and MSC-5046 Based on One Scaffold
Emma Carswell,Timo Heinrich,Carl Petersson,Jakub Gunera,Sakshi Garg,Daniel Schwarz,Sarah Schlesiger, Frank Fischer,Thomas Eichhorn, Mathew Calder, Geoffrey Smith, Ellen MacDonald, Hollie Wilson, Katherine Hazel,Elisabeth Trivier,Rebecca Broome,Alexander Balsiger, Sameer Sirohi,Djordje Musil,Filipe Freire,Heike Schilke,Christian Dillon,Dirk Wienke BIOORGANIC & MEDICINAL CHEMISTRY LETTERS（2024）
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Hippo pathway,TEAD inhibitor,TEAD selectivity,Oncology
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