Utilizing A Hydrophobic Primary Container Surface to Reduce the Formation of Subvisible Particles in Monoclonal Antibody Solution Caused by Fluid Shear

Xinyue Wang, Junjie Wang, Yang Han, Xingchun Jiang, Sixian Cao, Dongze Xu, Tiancheng Xiong, Xiang Guo, Cui Wang,Sha Guo, Hongying Song, Ting Dong, Le Zhang, Zhenming An,Jun Liu,Jing Han, Hao Wu

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS（2024）

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关键词

Monoclonal antibody,Subvisible particle,Primary container,Human complement,Protein aggregation,Interfaces

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