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Discovery of N-Aryl-N′-[4-(aryloxy)cyclohexyl]squaramide-Based Inhibitors of LXR/SREBP-1c Signaling Pathway Ameliorating Steatotic Liver Disease: Navigating the Role of SIRT6 Activation

Long Huu Nguyen,Ye Eun Cho,Soyeong Kim,Yeonsoo Kim,Jinsook Kwak,Jung-Soo Suh,Jinyoung Lee, Kyuwon Son, Minseong Kim, Eun Seo Jang, Naghyun Song, Buchul Choi, Jiah Kim, Yealin Tak, Taeyeon Hwang,Jeyun Jo,Eun-Woo Lee,Sang-Bum Kim, Sanghyun Kim,Oh-Bin Kwon,Sangok Kim,Seoung Rak Lee,Haeseung Lee, Tae-Jin Kim,Seonghwan Hwang,Hwayoung Yun

Journal of Medicinal Chemistry（2024）

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