PF-06952229, a Selective TGF-β-R1 Inhibitor: Preclinical Development and a First-in-human, Phase I, Dose-Escalation Study in Advanced Solid Tumors

T. A. Yap,A. D. Choudhury,E. Hamilton, L. S. Rosen, K. L. Stratton, M. S. Gordon, D. Schaer, L. Liu, L. Zhang, R. K. Mittapalli, W. Zhong, N. Soman,A. W. Tolcher

ESMO OPEN（2024）

引用 2|浏览5

关键词

TGF-beta-R1 inhibitor,advanced solid tumors,TGF-beta signaling,epithelial-mesenchymal transition,metastatic castration-resistant prostate cancer

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要