Evaluation of the Nitrosamine Impurities of ACE Inhibitors Using Computational, in Vitro, and in Vivo Methods Demonstrate No Genotoxic Potential.
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS（2024）
Key words
ACE inhibitors,duplex sequencing,genotoxicity,metabolism,NDSRI,nitrosamine,quantum chemical calculations,SAR,transgenic mutation
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