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Empowering the biomedical research community: Innovative SAS deployment on the All of Us Researcher Workbench.

Izabelle Humes,Cathy Shyr, Moira Dillon, Zhongjie Liu, Jennifer Peterson, Chris St Jeor, Jacqueline Malkes, Hiral Master, Brandy Mapes, Romuladus Azuine, Nakia Mack, Bassent Abdelbary, Joyonna Gamble-George,Emily Goldmann, Stephanie Cook, Fatemeh Choupani,Rubin Baskir, Sydney McMaster,Chris Lunt, Karriem Watson, Minnkyong Lee, Sophie Schwartz,Ruchi Munshi,David Glazer,Eric Banks,Anthony Philippakis, Melissa Basford,Dan Roden, Paul A Harris

Journal of the American Medical Informatics Association : JAMIA(2024)

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Abstract
OBJECTIVES:The All of Us Research Program is a precision medicine initiative aimed at establishing a vast, diverse biomedical database accessible through a cloud-based data analysis platform, the Researcher Workbench (RW). Our goal was to empower the research community by co-designing the implementation of SAS in the RW alongside researchers to enable broader use of All of Us data. MATERIALS AND METHODS:Researchers from various fields and with different SAS experience levels participated in co-designing the SAS implementation through user experience interviews. RESULTS:Feedback and lessons learned from user testing informed the final design of the SAS application. DISCUSSION:The co-design approach is critical for reducing technical barriers, broadening All of Us data use, and enhancing the user experience for data analysis on the RW. CONCLUSION:Our co-design approach successfully tailored the implementation of the SAS application to researchers' needs. This approach may inform future software implementations on the RW.
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