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Structure-guided Disulfide Engineering Restricts Antibody Conformation to Elicit TNFR Agonism

Isabel G Elliott,Hayden Fisher,H T Claude Chan,Tatyana Inzhelevskaya,C Ian Mockridge,Christine A Penfold,Patrick J Duriez,Christian M Orr,Julie Herniman, Kri T J Müller,Jonathan W Essex,Mark S Cragg,Ivo Tews

Nature communications（2025）

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