Identification of Potent and Reversible Piperidine Carboxamides That Are Species-Selective Orally Active Proteasome Inhibitors to Treat Malaria
Aloysus Lawong,Suraksha Gahalawat,Sneha Ray, Nhi Ho,Yan Han,Kurt E. Ward,Xiaoyi Deng,Zhe Chen,Ashwani Kumar,Chao Xing, Varun Hosangadi,Kate J. Fairhurst,Kyuto Tashiro,Glen Liszczak,David M. Shackleford,Kasiram Katneni,Gong Chen,Jessica Saunders,Elly Crighton, Arturo Casas, Joshua J. Robinson,Leah S. Imlay, Xiaoyu Zhang,Andrew Lemoff,Zhiyu Zhao,Inigo Angulo-Barturen,Maria Belen Jimenez-Diaz,Sergio Wittlin,Simon F. Campbell,David A. Fidock,Benoit Laleu,Susan A. Charman,Joseph M. Ready,Margaret A. Phillips Cell chemical biology（2024）
Key words
plasmodium,malaria,proteasome,drug discovery,drug resistance
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