Factors associated with pathological up-staging in MRI cT3a prostate cancer – a retrospective study from a high-volume centre
World Journal of Urology(2024)
摘要
Multiparametric MRI (mpMRI) parameters of pT3a prostate cancer have not been examined in large cohort studies. Therefore, we aimed to identify factors associated with up-staging of mpMRI cT3a in post-operative histopathological confirmation. Retrospective analysis of a prospectively maintained database of a single UK cancer centre. Only cT3a cases who underwent robotic-assisted radical prostatectomy (RARP) were included (N = 383). MRI and specimen histopathology was reviewed independently by expert uro-radiologists and uro-histopathologists, respectively. Factors included age, BMI, prostate-specific antigen (PSA) level, biopsy international society of urological pathology (ISUP) grade, Prostate Imaging Reporting Data System (PI-RADS®) score, tumour size, tumour coverage of gland (
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关键词
Advanced prostate cancer,Multiparametric MRI,Prostate cancer,TNM staging
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