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Ultrasensitive Detection of Aggregated Α-Synuclein Using Quiescent Seed Amplification Assay for the Diagnosis of Parkinson’s Disease

Hengxu Mao,Yaoyun Kuang,Du Feng,Xiang Chen,Lin Lu,Wencheng Xia, Tingting Gan,Weimeng Huang,Wenyuan Guo, Hancun Yi, Yirong Yang,Zhuohua Wu,Wei Dai, Hui Sun, Jieyuan Wu, Rui Zhang,Shenqing Zhang,Xiuli Lin,Yuxuan Yong,Xinling Yang, Hongyan Li,Wenjun Wu,Xiaoyun Huang,Zhaoxiang Bian,Hoi Leong Xavier Wong,Xin-Lu Wang,Michael Poppell,Yi Ren,Cong Liu,Wen-Quan Zou,Shengdi Chen,Ping-Yi Xu

Translational Neurodegeneration（2024）

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Key words
α-Synuclein,Seed amplification assay,Quiescent SAA,Parkinson's disease,Seeding activity
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