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Single-cell Decoding of Drug Induced Transcriptomic Reprogramming in Triple Negative Breast Cancers

Farhia Kabeer,Hoa Tran,Mirela Andronescu, Gurdeep Singh,Hakwoo Lee,Sohrab Salehi,Beixi Wang,Justina Biele,Jazmine Brimhall,David Gee,Viviana Cerda,Ciara O’Flanagan,Teresa Algara,Takako Kono,Sean Beatty,Elena Zaikova,Daniel Lai,Eric Lee,Richard Moore,Andrew J. Mungall,Marc J. Williams,Andrew Roth,Kieran R. Campbell,Sohrab P. Shah,Samuel Aparicio

GENOME BIOLOGY（2024）

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Key words
PDX,Single-cell RNA sequencing,DLP+ single-cell sequencing,Cisplatin treatment,In-cis/in-trans genes,Sensitive/resistant clones,Clone aware analysis
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