The correlation between corona virus disease 2019 and alopecia areata: a literature review

Ying Xie, Ying Xie, Shuying Lv, Shuying Lv, Sha Luo, Yuxuan Chen, Yuxuan Chen, Meijiao Du, Meijiao Du, Yonglong Xu, Yonglong Xu,Dingquan Yang

Frontiers in Immunology(2024)

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Abstract
Corona virus disease 2019(COVID-19) is one of the most serious respiratory pandemic diseases threatening human health for centuries. Alopecia areata (AA) is a sudden patchy hair loss, an autoimmune disease, which seriously affects the image and mental health of patients. Evidence shows that the risk of autoimmune diseases significantly increases after COVID-19, and is positively correlated with the severity, with a significant increase in the risk of alopecia in those over 40 years old. The relationship between COVID-19 and AA has become a hot topic of current research. Strengthening the research on the correlation between COVID-19 and AA can help to identify and protect susceptible populations at an early stage. This article reviews the research progress on the epidemiological background of COVID-19 and AA, the situation and possible mechanisms of AA induced by COVID-19 or COVID-19 vaccination, and potential treatment methods.
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Key words
COVID-19,alopecia areata,vaccination,correlation,pathogenesis,treatment
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