Prognostic significance of MRI contrast enhancement in newly diagnosed glioblastoma, IDH-wildtype according to WHO 2021 classification

Alexandre Roux, Angela Elia, Benoit Hudelist, Joseph Benzakoun, Edouard Dezamis, Eduardo Parraga,Alessandro Moiraghi, Giorgia Antonia Simboli, Fabrice Chretien, Catherine Oppenheim,Marc Zanello, Johan Pallud

Journal of Neuro-Oncology（2024）

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摘要

Contrast enhancement in glioblastoma, IDH-wildtype is common but not systematic. In the era of the WHO 2021 Classification of CNS Tumors, the prognostic impact of a contrast enhancement and the pattern of contrast enhancement is not clearly elucidated. We performed an observational, retrospective, single-centre cohort study at a tertiary neurosurgical oncology centre (January 2006 - December 2022). We screened adult patients with a newly-diagnosed glioblastoma, IDH-wildtype in order to assess the prognosis role of the contrast enhancement and the pattern of contrast enhancement. We included 1149 glioblastomas, IDH-wildtype: 26 (2.3

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关键词

Magnetic Resonance Imaging,Contrast enhancement,Glioblastoma,Neurosurgery,Survival analysis

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