A Novel Enantioselective Chitosan-Based Stationary Phase Prepared by Molecular Imprinting of a Racemic Template

Chromatographia(2024)

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Abstract
Chitosan is a chiral polyglucosamine polysaccharide that selectively binds to S-enantiomer of ketorolac rather than R-enantiomer. In this paper, a novel chiral stationary phase was prepared by molecular imprinting of chitosan using racemic ketorolac as a template. This imprinting process resulted in a high enantioselectivity (59.66
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Key words
Chiral stationary phases,Chiral molecularly imprinted polymer,Chitosan,Ketorolac,Racemic template
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