Tuning sensitivity of bimetallic, MXene and graphene-based SPR biosensors for rapid malaria detection: a numerical approach

Bhishma Karki,Arun Uniyal, Manoj Sharma,Ram Bharos Yadav, Parusharamulu Buduma

Journal of Computational Electronics(2024)

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Abstract
The potential of surface plasmon resonance (SPR) biosensors to detect different biomolecules quickly and sensitively has attracted much attention. In this work, we use a numerical method to identify malaria phases by exploring the sensitivity adjustment of SPR sensors based on bimetallic, MXene and graphene layers. Effective treatment for malaria, a potentially fatal disease brought on by plasmodium parasites, depends on early identification. Innovative biosensing technologies are necessary since traditional diagnostic procedures frequently lack sensitivity and speed. The transfer matrix method is employed here in this study for reflectance calculation. The COMSOL software finds the electric field distribution across the various layers interfaces. The maximum sensitivity of 301.1667°/RIU has been attained for the proposed work.
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Key words
Malaria detection,SPR sensor,Malaria detection,Sensitivity tuning,BK7 prism
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