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The Feasibility and Efficacy of a Virtual Reality Tandem Cycling Program for Persons with Parkinson’s Disease and Their Care Partners

Alia T. Sadek, Leila Djerdjour, Ryan A. Reyes, Greggory P. Adams, Cara H. Logan, Margaret A. Smith, Sara G. Biddle, Timothy S. Wiles,Enrique Urrea-Mendoza, Tracie M. McConnell,Fredy J. Revilla,Jennifer L. Trilk

Neurology and Therapy(2024)

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Abstract
Persons with Parkinson’s disease (PwPD) suffer from motor and non-motor symptoms which significantly affect their quality of life (QoL), and the QoL of their care partners (CP). Tandem cycling reduces PwPD motor symptoms; however, no studies have examined other benefits or included PwPD CP. We conducted an 8-week community virtual reality (VR) tandem cycling intervention to assess the feasibility and efficacy for PwPD and their CP (i.e., PD dyads). We hypothesized that dyadic tandem cycling would improve (1) PwPD motor and non-motor symptoms and (2) dimensions of PD dyads’ QoL and physiologic health. Ten PD dyads were recruited to complete 8 weeks of progressive intensity, bi-weekly tandem cycling. At pre- and post-testing, PwPD were assessed using the Movement Disorder Society–Unified Parkinson’s Disease Rating Scale-III (MDS-UPDRS-III), functional gait assessment (FGA), and 10-m gait speed test. PD dyads also completed emotional and cognitive status questionnaires [e.g., Geriatric Depression Scale-Short Form (GDS-SF)], and wore BodyGuard 2 heart rate (HR) monitors for 48 h to assess surrogate measures of heart rate variability. Statistical analyses were conducted using Student’s t tests with significance set at p ≤ 0.05. Eight PD dyads and one PwPD completed the intervention. Retention of PwPD (90
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Key words
Carers,Caregivers,Care partners,Cycling,Exercise intervention,Exercise program,Parkinson’s disease,Stationary cycling,Tandem cycling
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